Know the do’s & dont’s related to Jatenzo

Nowadays, the craze of the muscular body has boomed drastically. People are consuming Performance Enhancing Drugs (PEDs) for the same purpose, and even the people engaged in competitive bodybuilding and sports. One of the drugs that have come into the limelight for increasing muscle mass is known as Jatenzo. If you are here to know more about it, then you are at the right place. Let's discuss everything about this drug in-depth.

 

What is Jatenzo?

It is an androgen approved by the Food and Drug Administrative (FDA) for use in males to treat testosterone deficiency. It plays a vital role in maintaining sexual & reproductive features (males), muscle mass, bone density, etc. Sometimes, medical conditions like dysfunction or tumour of the pituitary gland, metabolic disorders, renal disorders, Kallman syndrome, Klinefelter syndrome, estrogen excess, etc., can lower down testosterone levels. The condition in which the testosterone level is lower than the normal range is called male hypogonadism.

Jatenzo is formulated with the active drug testosterone undecanoate (schedule iii controlled substance) and recommended for testosterone replacement therapy. The government of different countries have pre-determined rules and regulations on the usage of this drug.

When to use it?

As we discussed that this drug could help in boosting testosterone levels, there are some specific cases or symptoms when it is recommended. These are:

• Primary hypogonadism, including congenital or acquired

Indications: Testicular failure due to cryptorchidism, bilateral torsion, chemotherapy, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter syndrome, or toxic damage from alcohol or heavy metals

 

• Hypogonadotropic hypogonadism including congenital or acquired

Indications: Deficiency of Gonadotropin or luteinizing hormone-releasing hormone (LHRH) or pituitary-hypothalamic injury from tumours, trauma, or radiation.

 

Limitations

Safety standards for this medication are not formulated for males below the age of 18 years.

 

 

When shouldn't Jatenzo be consumed?

• Men who are diagnosed (or suspected) with carcinoma of the breast or prostate
• Women, especially pregnant women and lactating mothers       
• People allergic to this compound
• Men with hypogonadal conditions which are not related to structural or genetic etiologies

 

 

Precautions

• Increase in blood pressure

If the BP hikes during the consumption of Jatenzo, it can increase the risk of MACE. Hence the cardiological condition should be diagnosed before consumption of this drug.

• Polycythemia

Sometimes, an increase in the hematocrit reflective is observed in RBC mass, increasing the risk of thromboembolic events.

 

• Cardiovascular Risks

Some studies suggest that usage of Jatenzo can become a threat to cardiovascular health by increasing the risk of MACE.

 

• Benign Prostatic Hyperplasia (BPH) and Potential Risk of Prostate Cancer

Patients suffering from BPH are recommended not to consume androgens because it can worsen the case. Moreover, it can make the patients prone to prostate cancer.

 

• Venous Thromboembolism

Patients undergoing testosterone replacement drugs experience symptoms of venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE).

 

• Spermatogenesis

Androgens can suppress spermatogenesis, which can lead to negative results in semen parameters.

 

• Hepatic Adverse Effects

Patients taking this androgen for a long period shows symptoms of hepatic dysfunction (like jaundice).

 

• Edema

Androgens can lead to excessive sodium and water retention in the body, which can lead to many health complications, including edema.

 

Side effects

• Development of Gynecomastia (who are suffering from hypogonadism)
• Sleep apnea
• A negative change in the serum lipid profile
• Increased risk of hypercalcemia
• Disruption in hormones which can lead to the risk of depression and suicidal ideation
• Frequent headache
• Increase in serum PSA concentration

 

Conclusion

It is clear this drug is useful for treating testosterone deficiency, but there are many health complications that can develop after consuming it. So it is better to consume it under medical supervision.

 

 

 

Disclaimer 

This content is only for education, and we don'tdon't promote any felonious commodity. Please, please stay away from harmful commodities for the betterment of our Nation. Use any pharmaceutical drug under the supervision of a registered medical practitioner.

Jai Hind. 

Src:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/206089s000lbl.pdf

https://www.medicalnewstoday.com/articles/drugs-jatenzo